Sativa strains tend to provide more invigorating, uplifting cerebral effects that pair well with physical activity, social gatherings, and creative projects.
Sativa cannabis plants have thinner leaves and longer flowering cycles than their indica counterparts. They’re also taller: Some sativas can grow upwards of 25 feet, though most stay under 12 feet tall.
Although the main psychoactive constituent of Cannabis is tetrahydrocannabinol (THC), the plant is known to contain more than 500 compounds, among them at least 113 cannabinoids; however, most of these “minor” cannabinoids are only produced in trace amounts. Besides THC, another cannabinoid produced in high concentrations by some plants is cannabidiol (CBD), which is not psychoactive but has recently been shown to block the effect of THC in the nervous system. Differences in the chemical composition of Cannabis varieties may produce different effects in humans. Synthetic THC, called dronabinol, does not contain cannabidiol (CBD), cannabinol (CBN), or other cannabinoids, which is one reason why its pharmacological effects may differ significantly from those of natural Cannabis preparations.